deep blue sea (1999)

"What you've done is taken God's oldest killing machine and given it will and desire. What you've done is knocked us all the way to the bottom of the goddamn food chain. It's not a great leap forward in my book."
An isolated deep sea research station is home to a group of scientists, (including Thomas Jane, Saffron Burrows & Samuel L. Jackson), searching for a cure to Alzheimer's, using enzymes from giant Sharks. Unfortunately, as is usually the case, genetic mutating a killer species ends in a fight to the death, with the scientists becoming shark bait.
Well made thriller, with a decent amount of action, which off sets the lack of any real plot.